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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bd7043bade1da4c6e422b13586b84aaabbb215120de738969e54b372cb2d4d5' 
  AND token = 'LP3QdIiO+hE6Tfy5fKuHg+1HGGai1FQmn3Nk5KwTINI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}