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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b459f08f8da5dfc141b61f728b7a66710ad64aa2c49c7e96a6997b1059caf3' 
  AND token = 'lctAszRr7d/Mddy6RB3IRr/YD2IzmvQZPcB4JZN6kzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}