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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0f436a3312e1f52e3b36acb4678f711878d7a951932ad1b3e7739ae9dee994' 
  AND token = '+med31g/j8s9pm6jnfQ2VQjcqbNbimj3hbZ+bIWepD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}