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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a7c07e91b035d95786e493388abf67c89701a2b260df8e91a9dc5f2b1ad7c7f' 
  AND token = 'sgrPNHLTQ6dof9zMAHnf+cgRLgFZSfTI/exUR5OBPh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}