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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '846031860c7e01a8b5037fda95455d3a4370de80e329a4e2b18fb5e9a57217ba' 
  AND token = 's0oawtvHu9rinkDhif+dbx9k3aQ9B3kC45VZW6QCMkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}