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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4d5e3179593ed443e9fdc14138ca45d041ccd6c47c335d120bfc996b9b91e84' 
  AND token = 'lIbyBAM0tSok+2xcWR6ScJqckcDH7XymkH7KqedW4LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}