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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ac1d908201d9e751b8d13caa2e79d27b697f4e8a227d79495dfc3e49a8bf4f' 
  AND token = 'J5nkoqUTXbunZmLGRG7RX9h8yes6krRPiARuOAx0Cpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}