SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a32ce3771b6a48435ef09ee8894b5e69c55a78bc19bd43976a15118bd0c27122' 
  AND token = '08fQx0tYuqf2VF5qt+AlOdzruEhT12G7Gphq5lOEFy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}