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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9c7c21ffae03070022da437ad09e916ad61bfdd3d4fc7678e5519fd04c974ac' 
  AND token = '50S05ZzubtiZOxb+JMn4PPGZcICFHVbtFXTfmBB8JgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}