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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaf637723742ea0fc089e33c19fd024c0a8ce8dff7812b65b65a675c63478f4d' 
  AND token = 'qVjql7qlJM2Kme3b2JBVlpZ7zN2FoVmIbvQVT7CJmqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}