SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df5efa8c3fa0d2fd1c7a2d46969e08b1855c5768eb65a268f161f232e02eea54' 
  AND token = 'Xucqz4LyTOt0WDUZEi8clKYPVB11ofABpmtmDSyj78Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}