SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f5a44379cfc1f2545bb27f8f70d3902505312bba4bf52b65332a65e849dc15' 
  AND token = 'GRVV2Z2IrLpq+gtmwU1n07B8R9pVX1yhv81vP05NHhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}