SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c6a3ae39bc054fff405c238e2e28e58596d1c2ba096c46ba9e987daac0e7e5d' 
  AND token = 'l6iJmfGqBOKSnmr/VqgUXkfhdasW46S9TSsZK8pA54w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}