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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a1ca46660a42a9dc5b11f5b9542cf8ad1115f215ab002c75c430092659cc86f' 
  AND token = 'M46oZVhm0Xxh7L5zngwqWMAdpxdO1S0WAy32eIcVtUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}