SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f783b4de12e2756f744c84746c6bb6628e5a95b4562d03fad504d3c35f53735b' 
  AND token = 'pjZCwO/5GU7Tb4OrgwZiD2WV3L+p+8E6lm3SYkvAUdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}