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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543a3c3b5c59e226bb14960d2b0a80afd9ad763cface7973bb0e57bf1decd7b7' 
  AND token = 'zaP266G959t9l1iRqE7JJD7Byv3po4Af5/WBC3omW5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}