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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a624b7a40d07c75ffcc3a373dc3d41670a953fc7e2cd73ed982fe055616061f' 
  AND token = 'JAyVA+GsewXk9qQwoP/cbgJEaoo3VAAVaZCIzB84Tso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}