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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757dd8ef8c2ec2fbb2eb1a910546b7550b7a893eb61b05797a8a87b206a6fa66' 
  AND token = 'iWMU/kVehaVRVup3y57mBkoZJ42XA+VBZ0jB6sxiUus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}