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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee3621284c6b05afba0de5f50414224c3412b9dc0f2fa26b1389c605406dc4f3' 
  AND token = 'ytc1I37cF9CULznGzILoU2WDDFC9UfdK8XjgrEwFDlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}