SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e41b5cf4a57f66bb80dadbcce8241501a8ef15be2dbbc08666936a1b839e91d3' 
  AND token = 'cRERLtmhjMMB+XEXazRBN2AbjFN2ldhN24NGtutkU2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}