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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2f6e4746fd24b3e86962505156b6a547b33269a0ebbb77994ca36c3a6034a5c' 
  AND token = '7UJcBM6k6w0dI4VvrWWHhcFAZpynmMYp6XP4kUomNaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}