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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e5ab0e61735af95e0f2892ba5726a886e6ca1320a173b58c562fbcb8b686908' 
  AND token = 'pv/uvTrgqjHDewvnGuD0C9VMimDdcQn2ub/nA/6n0Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}