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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49c35b54c3157f859ea8f3cac985d0ad3218eba4105d38588d93f2527d2095a' 
  AND token = 'X9zC8lfKIh9Nqf69tn8KxXdwet6FRExX7l9326xzMzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}