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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1469082d5177d4fe70d59f4cdc78d3a5ad66de24f55c88b9a076e1addaaa52d0' 
  AND token = 'z3vmHRIZw8Ko2Evy+8MUKJrROhI7djZszt2b+yRHcm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}