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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c28f470ad88f8f45398459ffa9e2d3c54f71b88b9105ac3c8ffcdaef1683cb8' 
  AND token = 'tNAdREY0NTEKHE5z8+Oa3Q8p5AZr34s8D5uLdI8qOcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}