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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b646b704ef72f9ee3fe36dead3d531208cf30dbf052b90be04343bd3ee0f61b' 
  AND token = 'gUHvhDRxl2JSkiBwc/NBWEydc37Se1Xx0S0EMg2LD4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}