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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37c4a755b3acf828df25783c0194d7f714d4d1878eb11c7758d438cbb0367fe7' 
  AND token = 'huX/i0VxlMDeAaQH4Vhx09ZZ2N7uhksHgJ5EnSNhyG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}