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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32ef6e48210b06eb953c7fd59add7bc816aed5c1cc8b839fa71eca9952476a11' 
  AND token = 'RVkPtvgkYkHhFpSo0c8VvLfHN3yrk1Y2HF47NnKQqDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}