SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ea237151e1f893f1c2db53497f5462601b5182b9945e6eb6a60ce1eb990311' 
  AND token = '0NoO/0SbF1uM8yRawF6SWAmUIizZzXk2JkwGZK9ixMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}