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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de08753c8b9bd14d00544df3c854d91e312de6db0100d42e1d2152f8a2e53b8a' 
  AND token = 'qD/9yn/CXz7UJ7wuE2mWIICI14rpSmNQ4IU460f01YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}