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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d07a8897173fea4254a75b38250f4627fd500d001ef76e8ac144b1ce44669fa' 
  AND token = 'gyqDp1v6uiwxe3+iHVaz1IjmFnvQ+wam67ctrSSvlsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}