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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '992446739a29a4d1d89eb7e6a98171e8ae9d2c2f8644175a6d97a5a61672e708' 
  AND token = 'zE+eCi6joHYdDCB8aHXQT5MM3NFd4VFbV5n0yofb2Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}