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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072e0e2f12d5ddd8f99d79d30e41a5d615b2f3f19001bec9eb924a46706b58fe' 
  AND token = '+rnPRi53MDS25DjbdfgUz35dPqe8cpyIUv7sEQ1x2Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}