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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4d3bbbc89d564e06da3da4dede42c8c22a08eed01eb18a9fd09844c895c965' 
  AND token = '7k3LnV8O+wkCzhU3ViqZcVHH+FAJR9IBA0RbpXq9608=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}