SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e87a277e9dc5a893ad45b35cbb4377b7d749de47e9a1826ccd606989b9f33b2' 
  AND token = 'pthOndyzH4pWNIOYA2OLyczuQ4t5g/3cjLJ8HGusamM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}