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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df42a27aaa77863d8cbbbb449aa2abc4460a99b3947bc2beb8c99b38415e7b4' 
  AND token = 'oXisR0ts2kcEavxHwdWBtfM6h+hunklxEZoxOBoUieM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}