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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0335551b4a97f3407ec3c5c0f9935af5ebeb04da708727f48d0f6ba296cea70a' 
  AND token = 'UdZ20RkO60r9ia93AyxJu7N+orLoMJeIB33rcfc6Dxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}