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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3640269548b1a1da68412ad980ff8e8cb141ff954e2c46b1bdfe063046002742' 
  AND token = 'AXuTHZs0tLf64Nyh9qpoUTGr7lm2Ga1Fj1PD8wf6C4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}