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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343ee16455897bbde85977894e32ed8e7bbbc8ed1846dbdb9af41e42ff650019' 
  AND token = 'MW29hZaVHYlPLLSkBa3XPvPVQUuKIgk8d3aXHpAq9Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}