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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41f617eaa6df238f167cccfcac68f83910aa4f6bdf591278ef80723f3605ee3' 
  AND token = 'krEgjHhHzM4fxXb5t4ebVDx2uW+0LDuX4nnPjI4X/1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}