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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '835cdc76b683e5d2476ec04692cfd33f425920071ee18bb042664bab52f4a3cd' 
  AND token = 'RhsrD/oKv+LZQDAy0AEDkNoDL0z2g7dh5Dz9W70LUWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}