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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f747595c8f87c119c8e90715acaba1f559ec96e77d007cc0208174587f72e931' 
  AND token = 'S/zDL6BTdN3mqqjoBQeXbAlb0qLdQhh8nvLoNurCr9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}