SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e665ca8ffe04dd6be01c0502d78e431018da4fff4dee4b6a1bf992cf4bb1bf6' 
  AND token = 'inmzabFwd8LKqJRtmx9r1i6drTbpUAdwIadIrFS1rPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}