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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f146c43d64af1a2cb435881cd44f318506ab4ee70bf2cb5cfa3b9547dc6a87' 
  AND token = '+pOJHjRfWkZ71pCrJd0JThtb1ekihGaq5dgrY93JkTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}