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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b402e373b1ac159fa42e14cbe3276b06b468782142698380b30df0d9f808fb2c' 
  AND token = 'rR3+BZMB1m3O1bZUo16sO0Q7ipsvHBfDCO0JpYMRNBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}