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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc32c7de6c27754617dd3aaf038c6e20c8bbed5501b36249bdfade973088fa7' 
  AND token = 'S6v3fAUU6QbEKN5YnkZZRVi7OZhYdeUYa6pfIYqu9Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}