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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '642dcfc2dbd5ec7c8106624592d2ac9d35ddf40757c942c131d3562e2ff02165' 
  AND token = 'tQ0Q+j29A2gQ5V64NwYtpSTE6+3cN+252+R+Sp+k2G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}