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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9d2acd37454f93ea6ed0e274a3bbffdac6c0e5f319c51a635aa68522e9e1777' 
  AND token = 'S4+3hKCgicvmFN/EBtAcMrdXzx2S8R2s55x0R+ZTisc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}