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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '615165a5d6966919eaa5376eb29294daa237e6f96f9130acc3c30bc155381134' 
  AND token = 'AXLFegem5AtgXB5eG+NCMMJJzH9bCpqNIBiqYIsEm18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}