SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8eacf94f405387074493f8f34e2d2e3ac664caff5d830b1940b49a389d560b' 
  AND token = 'Rm6bX2EIpWD9OBmPAU3qYDCevkTxYW0ndrgGV6Q3kPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}